pyridoxal isonicotinoyl hydrazone
- Product Name
- pyridoxal isonicotinoyl hydrazone
- CAS No.
- 737-86-0
- Chemical Name
- pyridoxal isonicotinoyl hydrazone
- Synonyms
- NSC 77674;PIH - CAS 737-86-0 - Calbiochem;Pyridoxal isonicotinoyl hydrazine;PIH(Pyridoxal isonicotinoyl hydrazine);Pyridoxal isonicotinoyl hydrazone (PIH);inhibit,pyridoxal isonicotinoyl hydrazone,Inhibitor;N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide;N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide;4-Pyridinecarboxylic acid, 2-[[3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl]methylene]hydrazide
- CBNumber
- CB31370372
- Molecular Formula
- C14H14N4O3
- Formula Weight
- 286.29
- MOL File
- 737-86-0.mol
pyridoxal isonicotinoyl hydrazone Property
- Melting point:
- 261-262 °C (decomp)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- +2C to +8C
- solubility
- DMF: 1 mg/ml; DMSO: 5 mg/ml; Ethanol: 0.5 mg/ml
- form
- Yellow solid
- pka
- 8.04±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 528110-M
- Product name
- PIH - CAS 737-86-0 - Calbiochem
- Purity
- A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class.
- Packaging
- 528110-50MG
- Price
- $275
- Updated
- 2024/03/01
- Product number
- 528110-M
- Product name
- PIH - CAS 737-86-0 - Calbiochem
- Purity
- A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class.
- Packaging
- 50mg
- Price
- $210
- Updated
- 2022/05/15
- Product number
- 19357
- Product name
- Pyridoxal isonicotinoyl hydrazone
- Purity
- ≥99%
- Packaging
- 50mg
- Price
- $141
- Updated
- 2024/03/01
- Product number
- P991723
- Product name
- PyridoxalIsonicotinoylHydrazone
- Packaging
- 100mg
- Price
- $335
- Updated
- 2021/12/16
- Product number
- B6060
- Product name
- Pyridoxalisonicotinoylhydrazone
- Packaging
- 50mg
- Price
- $105
- Updated
- 2021/12/16
pyridoxal isonicotinoyl hydrazone Chemical Properties,Usage,Production
Uses
Pyridoxal Isonicotinoyl Hydrazone is a cell-permeable non-toxic iron chelator of the aroyl hydrazone class.
General Description
A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class. Even at low concentrations, highly effective in mobilizing Fe3+ from cells and preventing its uptake from transferrin, even at low concentrations. Exhibits similar specificity and binding affinity as Deferoxamine Mesylate (Cat. No. 252750) but has greater access to mitochondrial iron. Also useful for the management of iron overload disease in experimental models. Inhibits the induction of heme containing indoleamine 2,3-dioxygenase activity.
pyridoxal isonicotinoyl hydrazone Preparation Products And Raw materials
Raw materials
Preparation Products
pyridoxal isonicotinoyl hydrazone Suppliers
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